Markham, Ontario · Physician-performed

PRP Therapy in Markham

PRP uses your body's own concentrated growth factors to stimulate natural healing and tissue regeneration. It is an effective treatment for hair restoration, helping to improve hair thickness and reduce shedding, under-eye rejuvenation, improving skin quality and fine lines, and joint pain, supporting healing and reducing discomfort associated with tendon and joint injuries.

Price

from $600

Appointment

60 minutes

Performed by

Dr. Mazzuca, MD

Location

Markham, ON

Book a Consultation   Book Platelet Rich Plasma (PRP) directly

Quick answer

PRP in Markham at Dr. Monique Mazzuca Aesthetics starts at $600 per session and is drawn, prepared and injected personally by a licensed physician. A small sample of your own blood is spun to concentrate the platelets, then the platelet-rich plasma is injected into the scalp for hair thinning, under the eyes and into the skin for rejuvenation, or into joints and tendons for pain. Most protocols are 3 sessions about a month apart, with results building over 3 to 6 months and maintenance every 6 to 12 months.

What PRP is

Platelet-rich plasma (PRP) is a concentrate made from your own blood. Platelets are the small cells responsible for clotting, but they also carry hundreds of growth factors (PDGF, VEGF, TGF-beta, EGF and others) that signal tissue to repair, grow new blood vessels and build collagen. A standard tube of blood is spun in a centrifuge to separate the red cells, leaving a golden plasma with three to five times the normal platelet concentration. Because it comes entirely from you, there is nothing to be allergic to and nothing synthetic is introduced.

PRP has been used in orthopaedics and sports medicine for decades and, more recently, in dermatology and hair restoration. Dr. Mazzuca uses it in four ways: scalp injections for hair thinning, under-eye and facial injections for rejuvenation, topical application with microneedling, and joint or tendon injections for pain.

How PRP works

When PRP is injected into tissue, the platelets activate and release their growth factors over several days. In the scalp, those signals prolong the growth phase of hair follicles, improve blood supply and can reawaken miniaturised follicles that are still alive. In the skin, they stimulate fibroblasts to make collagen and elastin and improve microcirculation, which is why under-eye hollows and crepey skin look brighter and firmer over time. In a joint or tendon, they recruit repair cells and modulate inflammation.

PRP is regenerative rather than instant: it asks your tissue to rebuild itself, so results arrive over weeks to months and depend on the health of the tissue being treated. That is also why it is repeated in a short series and then maintained.

PRP for hair loss and thinning

PRP is best for androgenetic (pattern) hair loss in men and women, and for diffuse thinning where follicles are shrinking but still present. A 2025 systematic review of 43 randomised trials (1,877 patients) concluded that PRP is safe and effective at increasing hair density and reducing shedding compared with placebo, with moderate-quality evidence. It does not regrow hair from follicles that have been dead for years, which is why earlier treatment gives better results. It can be combined with minoxidil, finasteride or other medical therapy, and Dr. Mazzuca, as a physician, can prescribe and manage those alongside PRP.

The usual protocol is three or four monthly sessions, then a maintenance session every four to six months. Shedding typically reduces within the first two months; visible thickening takes three to six months. Patients with scarring alopecia, alopecia areata or hair loss from thyroid disease, iron deficiency or medication need a medical work-up first, which Dr. Mazzuca can arrange.

PRP for under-eyes and skin rejuvenation

The under-eye area is thin and unforgiving: filler can look puffy or bluish there, and lasers are limited. PRP is a gentle alternative that improves the crepey texture, fine lines and dark, tired look of the lower eyelid by thickening the skin and improving circulation over a series of treatments. It is also injected as a "skin booster" across the cheeks, around the mouth, on the neck and on the backs of the hands, and it is applied topically after microneedling (the "vampire facial") for a brighter, smoother complexion.

PRP does not add volume the way a hyaluronic acid filler does. For a hollow tear trough, Dr. Mazzuca may recommend PRP alone, a small amount of filler alone, or PRP first and filler later, depending on your anatomy; see the under-eye page for how she decides.

PRP for joints and tendons

PRP is used in sports and musculoskeletal medicine for osteoarthritis of the knee, hip, shoulder and hands, and for chronic tendinopathies such as tennis elbow, golfer's elbow, patellar and Achilles tendinopathy and plantar fasciitis. Multiple randomised trials in knee osteoarthritis show PRP can reduce pain and improve function for six to twelve months, with several head-to-head studies finding it lasts longer than a cortisone or hyaluronic acid injection, although results vary and the evidence is still evolving. PRP does not rebuild lost cartilage and is not a substitute for a joint replacement in advanced disease.

Because Dr. Mazzuca is a physician, joint PRP begins with a proper history and examination and, where needed, imaging. Full details are on the joint regenerative therapy page.

How many PRP sessions you need

Treatment	Initial series	Maintenance
Hair thinning	3 to 4 sessions, 4 weeks apart	Every 4 to 6 months
Under-eyes	3 sessions, 4 to 6 weeks apart	Every 6 to 12 months
Skin rejuvenation / with microneedling	3 sessions, 4 weeks apart	Every 6 months
Joint or tendon	1 to 3 injections, 2 to 4 weeks apart	As needed, often 6 to 12 months

How much PRP costs in Markham

PRP with Dr. Mazzuca starts at $600 per session, with the appointment booked for 60 minutes to allow for the blood draw, preparation and injection. PRP for hair loss is listed from $450 (45 minutes) and joint PRP from $600. Series pricing is discussed at your consultation. New patients begin with the $50 Comprehensive Aesthetic Consultation or a $20 virtual consultation. Cosmetic PRP is not covered by OHIP; PRP for musculoskeletal conditions may be eligible under some extended health plans, so ask your insurer.

Across the GTA, physician-performed PRP generally costs $500 to $1,200 per session. Very low-priced PRP is often prepared with low-concentration kits or performed by non-medical staff.

Who PRP is for, and who should wait

Good candidates are adults in reasonable health with early to moderate hair thinning, tired or crepey under-eyes, dull skin, or joint and tendon pain that has not responded to rest and physiotherapy. PRP is also a natural fit for patients who want to avoid synthetic products.

PRP is not offered if you have a platelet disorder or low platelet count, a blood-borne infection, an active cancer or a history of blood cancer, are on chemotherapy, take blood thinners that cannot be paused, or are pregnant. Heavy smokers and patients with uncontrolled diabetes respond less well because their platelets are less effective. Anti-inflammatory medications (ibuprofen, naproxen) are paused for a week before and two weeks after treatment because they blunt the healing response.

What the appointment is like

1. Blood draw. One or two small tubes are drawn from your arm, the same as a routine blood test.
2. Preparation. The tubes are spun in a centrifuge for about 10 minutes, and the platelet-rich layer is drawn off and, where appropriate, activated.
3. Numbing. Topical anaesthetic for the face and scalp; local anaesthetic for joints if needed.
4. Injection. Many small, shallow injections across the scalp or skin, or a single guided injection into a joint or tendon. The scalp takes about 15 minutes.
5. Home. The entire visit is under an hour. Scalp patients can drive themselves; joint patients may prefer a ride.

Results timeline

PRP does not deliver an overnight result. Hair: less shedding by month two, visible thickening at three to six months, best result at six to nine months after the series. Under-eyes and skin: brighter and more hydrated within two weeks, with progressive improvement in texture and fine lines over three months. Joints and tendons: some soreness for the first week, then gradual improvement in pain and function over four to eight weeks, often lasting six to twelve months.

Results last as long as the tissue you rebuilt, which is why maintenance sessions are recommended, and why PRP works best alongside a good medical plan (for hair) or physiotherapy (for joints).

Side effects and safety

Because PRP is your own blood, allergic reaction and rejection are not a concern. Expected effects are tenderness, swelling, redness and small bruises at the injection sites for one to three days, a tight or "full" feeling in the scalp for a day, and, for joints, a flare of aching for two to seven days as the healing response begins. Rare risks are infection, nerve irritation and, for joints, a temporary increase in stiffness. Sterile technique and a physician's assessment keep these risks very low.

Aftercare

• Avoid anti-inflammatories (ibuprofen, naproxen, aspirin) for two weeks; use acetaminophen if needed.
• Scalp: do not wash your hair for 12 to 24 hours; avoid colouring or chemical treatments for one week; resume minoxidil the next day.
• Face and under-eyes: no makeup for 24 hours, no strenuous exercise, saunas or alcohol for 24 to 48 hours, and no retinol or acids for a few days. Sleep with your head slightly elevated the first night.
• Joints: relative rest for 48 hours, then gentle movement; avoid heavy loading for one to two weeks and follow the physiotherapy plan you were given.
• Ice can be used for comfort, but not heat in the first 48 hours.

PRP vs PRF, filler, minoxidil and cortisone

Option	What it is	When Dr. Mazzuca recommends it
PRP	Concentrated platelets in plasma	Hair thinning, under-eyes, skin quality, joints; results over months; no foreign material
PRF	A slower, lower-spin preparation that forms a fibrin scaffold and releases growth factors more gradually	Under-eyes and skin, where a gel-like consistency and prolonged release are helpful; used interchangeably with PRP depending on the goal
Hyaluronic acid filler	An injectable gel that adds volume immediately	True hollowing or loss of structure; immediate and dissolvable; not for skin quality
Minoxidil / finasteride	Prescription medical therapy for pattern hair loss	Almost always alongside PRP for hair; Dr. Mazzuca can prescribe and monitor
Cortisone injection	A steroid anti-inflammatory	Fast, short-term relief in joints; repeated use can weaken tissue, so PRP is often preferred for longer-term management

Why patients choose a physician for PRP in Markham

PRP involves drawing blood, preparing a biologic product and injecting it, sometimes into a joint. In Ontario, that is a medical procedure. At this clinic it is performed start to finish by Dr. Mazzuca, a licensed physician (MD, CCFP) with additional training in cosmetic medicine and facial anatomy, who can also diagnose the cause of your hair loss or joint pain, order tests, prescribe adjunct medication and manage any complication. Treatment is never delegated.

PRP near you: serving Markham and York Region

The clinic is at 200 Cachet Woods Court, Suite 309, in the Cachet Woods professional buildings near Woodbine Avenue and Major Mackenzie Drive, with free parking on site. Patients visit from Unionville, Cachet, Angus Glen, Berczy Village, Cornell, Wismer, Markham Village, Thornhill, Richmond Hill, Stouffville, Vaughan, Aurora, Newmarket, North York, Scarborough and across the Greater Toronto Area.

Frequently asked questions about PRP in Markham

Sources and further reading

• Platelet-Rich Plasma in the Management of Alopecia: systematic review and meta-analysis of 43 RCTs (Dermatology and Therapy, 2025)
• Gupta et al., PRP in hair restoration and facial aesthetics: systematic review and meta-analysis (J Cutan Med Surg, 2019)
• Is autologous PRP capable of increasing hair density in androgenic alopecia? Meta-analysis of RCTs (PMC, 2024)
• College of Physicians and Surgeons of Ontario, public register.

Every treatment on this page is booked through Dr. Mazzuca's secure online system. New patients begin with a consultation; returning patients can book the treatment directly.

Written and medically reviewed by Dr. Monique Mazzuca, MD, CCFP. Last reviewed 2026-09-07.

This page is general information, not medical advice, and it is not a substitute for an in-person assessment. Results vary between patients, and every treatment carries risks that are reviewed with you before you consent. Suitability is determined by Dr. Mazzuca at your consultation.

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